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Clinical Trials/NCT05115357
NCT05115357
Unknown
Not Applicable

Efficacy of Ultrasound-Guided Pecto-Intercostal Fascial Block Versus Transversus Thoracic Muscle Plane Block for Postoperative Analgesia in Cardiac Surgery

Tanta University1 site in 1 country90 target enrollmentDecember 24, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pecto-Intercostal Fascial Block
Sponsor
Tanta University
Enrollment
90
Locations
1
Primary Endpoint
Post-operative pain score
Last Updated
4 years ago

Overview

Brief Summary

The aim of this study is to compare the effect of Ultrasound-Guided Pecto-Intercostal Fascial Block versus Transversus Thoracis Muscle Plane Block on Postoperative Pain Analgesia in Cardiac Surgery

Detailed Description

Perioperative pain management is an essential component of the enhanced recovery pathway in patients undergoing cardiac surgery. The incidence of severe acute postoperative pain after median sternotomy is as high as 49%.

Registry
clinicaltrials.gov
Start Date
December 24, 2021
End Date
December 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Abdullah Nabeih Abdullah Eloraby

Assistant lecturer of Anesthesiology and Surgical Intensive Care and Pain Medicine

Tanta University

Eligibility Criteria

Inclusion Criteria

  • 90 adult patients of both sexes aged (21-60) scheduled for cardio-pulmonary bypass cardiac surgery (valve replacement) with midline sternotomy

Exclusion Criteria

  • Patients' refusal.
  • Cognitive impairment.
  • History of drug abuse\& chronic analgesic use
  • History of allergy to local anesthetics.
  • Emergency surgery
  • Pre-existing major organ dysfunction including hepatic or renal failure, pulmonary insufficiency and left ventricular ejection fraction \< 30%
  • Known coagulopathy

Outcomes

Primary Outcomes

Post-operative pain score

Time Frame: 24 hours postoperative

After extubation, patients will be evaluated for pain using numeric rating scale (NRS) score at 0,3,6,12,24 h for pain that ranged from (0 = no pain) to (10 = the worst imaginable pain). If score is ≥ 4, rescue analgesia will be given in the form of fentanyl in a dose of 0.5µg/kg by iv route.

Secondary Outcomes

  • Total opioid consumption in first 24 hours after cardiac surgery(24 hours Postoperative)
  • duration of mechanical ventilation(24 hours Postoperative)
  • Incidence of complications(24 hours Postoperative)

Study Sites (1)

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