Efficacy of Ultrasound-Guided Pecto-Intercostal Fascial Block Versus Transversus Thoracic Muscle Plane Block for Postoperative Analgesia in Cardiac Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Post-operative pain score
研究概览
简要总结
The aim of this study is to compare the effect of Ultrasound-Guided Pecto-Intercostal Fascial Block versus Transversus Thoracis Muscle Plane Block on Postoperative Pain Analgesia in Cardiac Surgery
详细描述
Perioperative pain management is an essential component of the enhanced recovery pathway in patients undergoing cardiac surgery. The incidence of severe acute postoperative pain after median sternotomy is as high as 49%.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •90 adult patients of both sexes aged (21-60) scheduled for cardio-pulmonary bypass cardiac surgery (valve replacement) with midline sternotomy
排除标准
- •Patients' refusal.
- •Cognitive impairment.
- •History of drug abuse& chronic analgesic use
- •History of allergy to local anesthetics.
- •Emergency surgery
- •Pre-existing major organ dysfunction including hepatic or renal failure, pulmonary insufficiency and left ventricular ejection fraction < 30%
- •Known coagulopathy
结局指标
主要结局
Post-operative pain score
时间窗: 24 hours postoperative
After extubation, patients will be evaluated for pain using numeric rating scale (NRS) score at 0,3,6,12,24 h for pain that ranged from (0 = no pain) to (10 = the worst imaginable pain). If score is ≥ 4, rescue analgesia will be given in the form of fentanyl in a dose of 0.5µg/kg by iv route.
次要结局
- Total opioid consumption in first 24 hours after cardiac surgery(24 hours Postoperative)
- duration of mechanical ventilation(24 hours Postoperative)
- Incidence of complications(24 hours Postoperative)
研究者
Abdullah Nabeih Abdullah Eloraby
Assistant lecturer of Anesthesiology and Surgical Intensive Care and Pain Medicine
Tanta University