Effect of high-dose oral N-acetylcysteine versus placebo on serum level of inflammatory cytokines in patients with ischemic stroke
Phase 2
- Conditions
- Ischemic stroke.Cerebral infarction
- Registration Number
- IRCT20120215009014N215
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Age of 18 to 85 years
Ischemic stroke
Stroke for the first time
Local neurologic disorder
Hospitalization within the first 24 hours after stroke
Exclusion Criteria
Pregnancy or breastfeeding
Inflammatory disease
Asthma
A history of anaphylaxis shock
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measuring serum level of TNF-a. Timepoint: Before intervention and 3 days later. Method of measurement: Through laboratory test.;Measuring serum level of IL-6. Timepoint: Before intervention and 3 days later. Method of measurement: Through laboratory test.;Measuring serum level of ICAM-1. Timepoint: Before intervention and 3 days later. Method of measurement: Through laboratory test.;Measuring serum level of NSE. Timepoint: Before intervention and 3 days later. Method of measurement: Through laboratory test.
- Secondary Outcome Measures
Name Time Method