Seeking the link between extracranial carotid artery aneurysms and small vessel disease

Recruiting

• Conditions: dilated carotid artery; extracraniel carotid aneurysm; 10002363

• Registration Number: NL-OMON51931
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Extracranial carotis artery aneurysm

Exclusion Criteria

Contra-indication for MRI
Age <18 years

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Presence of small vessel disease (i.e. WMH, lacunes, microbleeds, perivascular<br /><br>spaces, and recent small subcortical infarcts)) on 3 tesla brain MRI in ECAA<br /><br>patients measured by number, volume and localization.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Progression of smalle vessel disease over time<br /><br>- Small vessel disease related brain imaging features on brain MRI related to<br /><br>carotid aneurysm size (maximum diameter) based on previous CT/MRI imaging<br /><br>- Silent brain infarcts on brain MRI measured by number, volume and localization<br /><br>- Pulsatility and distensibility of the carotid wall</p><br>