A comparative study of targeted end-tidal carbon dioxide (EtCO2) versus standard EtCO2 management to guide resuscitation in emergency department cardiac arrest: a randomized controlled trial
Phase 2
Recruiting
- Conditions
- Patients experiencing cardiac arrest in the emergency department (EDCA). This includes patients who experienced their first cardiac arrest outside the hospital (OHCA) and then had a recurrent arrest in the emergency department, as well as patients who experienced their first cardiac arrest while already in the emergency department (IHCA).end-tidal carbon dioxide, targeted EtCO2, emergency department cardiac arrest, ROSC, high-quality CPR, improving mortality, reducing mortality
- Registration Number
- TCTR20240619001
- Lead Sponsor
- Thammasat University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
All patients who experience cardiac arrest in the emergency department (EDCA).
Exclusion Criteria
1. Patients younger than 15 years.
2. Cardiac arrest caused by traumatic events.
3. Patients with a do not attempt resuscitate (DNAR) order.
4. Patients showing signs of irreversible death (Livor mortis, Rigor mortis, decapitation, transection, decomposition).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sustained Return of spontaneous circulation Immediately after CPR Sustained ROSC is defined with any of the following for over 20 minutes: palpable carotid pulse, measurable blood pressure, or spontaneous movement by the patient. All without chest compression.,Survival to hospital discharge 30 days after CPR Case record form
- Secondary Outcome Measures
Name Time Method Survival with favorable neurological outcome 30 days after CPR Favorable neurological outcome is defined as a patient's recovery with minimal or no neurological deficits, quantified using Cerebral Performance Category Scale: CPC 1 or CPC 2