Treatment of Obsessive compulsive symptoms in Psychotic disorders: Cognitive Behavioural Therapy
- Conditions
- obsessive-compulsive disorderOCD in psychosis10002861
- Registration Number
- NL-OMON42610
- Lead Sponsor
- Psychiatrie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 88
1) Obsessive-compulsive symptoms (YBOCS * 12 for at least 2 months)
2) Age range of 18 to 50 years
3) Diagnosis of a schizophrenia spectrum disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5
5) Good command of the Dutch language
6) Able and willing to give written informed consent
1) Rumination or repetitive behaviour solely related to psychotic symptoms. Positive symptoms as such are not an exclusion criterion; only when they are considered to be the primary cause of OCS-like symptoms or when they are so severe that primary treatment focused on positive symptoms is called for (more than one PANSS item of the positive subscale has a score of 5 or when one PANSS item of the positive subscale has a score of 6 or more).
2) Sever intellectual impairment, defined as an estimated IQ<70
3) Psychopathology precipitated by an organic cause
4) High suicidality, operationalized as having a high suicidality score on the M.I.N.I. with the last suicide attempt within the past six months.
5) Changes in medication (mood regulators, antipsychotics) within one months prior to the inclusion of the study
6) Not being able to travel
7) Participant is in seclusion or admitted to a closed ward.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary endpoint is the change in OCS severity as assessed by the<br /><br>Yale-Brown-Obsessive-Compulsive Scale (YBOCS) compared to the waiting list<br /><br>condition. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary endpoints are changes in symptoms of psychosis and depression, social<br /><br>functioning, and quality of life.</p><br>