Obsessive compulsive symptoms in psychosis: Insight into dynamic interaction and symptom variability

Completed

Conditions: psychotic disorders
schizophrenia
10039628

Registration Number: NL-OMON38485

Lead Sponsor: Academisch Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 220

Inclusion Criteria

1) former GROUP participants, who have given informed consent to be contacted for future studies
2) Age range of 18 to 60 years
3) Diagnosis of non-affective psychotic disorder according to the Diagnostic and Statistical Manual of Mental Disorders
4) Previously reported co-morbid obsessive-compulsive symptoms
5) Good command of the Dutch language
6) Able and willing to give written informed consent
7) Internet access.
Additional Inclusion criterion for the experience sampling approach will be the change in OCS severity during the previous month. Significant change is defined as a delta Y-BOCS score of 5 or more.

Exclusion Criteria

1) IQ<60
2) Evidence of psychotic symptoms precipitated by an organic cause
3) Psychotic symptoms resulting from alcohol or drug dependence

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Web-based assessments with monthly assessment intervals over 12 months<br /><br>including psychopathology (psychosis, OCS and affective symptoms),<br /><br>environmental and individual factors (such as life events and coping<br /><br>strategies). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Subsequent use of the experience sampling method (ESM) over a period of 6 days<br /><br>in a subgroup of patients with a non-affective psychosis, who recently reported<br /><br>changes in OCS severity. </p><br>