Development of pharmacokinetic model for the target-concentration controlled infusion of cefoxitin used as a prophylactic antibiotic in surgical patients
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0004442
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 31
? Patients over 20 to 80 years old
? Patients scheduled to undergo colorectal or rectal surgery at Asan Medical Center
? Patients with physical status of the American Society of Anesthesiologists, Class 1-3
? Patients who weigh 40 kg or more
? Patients scheduled to receive cefoxitin as a prophylactic antibiotic
? Patients who have agreed in writing to voluntarily participate in this clinical study
? Pregnant or breastfeeding women
? Patients with a history of hypersensitivity to cefoxitin
? Patients with a history of cefoxitin given within 3 days of the scheduled operation time
? Patients with hemoglobin <8 g / dl
? Estimated glomerular filtration rate measured before surgery <60 ml / min
? Patients who received other clinical trial drugs within 7 days of the surgery
? Patients deemed inappropriate by investigators
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method pharmacokinetic parameter (volume of distribution, cleracne)
- Secondary Outcome Measures
Name Time Method adverse event