Pharmacokinetic and pharmacodynamic modelling of routinely used off label drugs in premature neonates

Completed

• Conditions: Pijn en sedatie; Prematurity; 10039911; 10028971

• Registration Number: NL-OMON44214
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 600

Inclusion Criteria

* Gestational age < 32 weeks
* Admitted to 1 of the participating NICUs
* Use of one of the studied drugs as standard of care
* Signed Informed Consent by both parents or guardians

Exclusion Criteria

None

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>1) Pharmacokinetic endpoints are clearance en volume of distribution. </p><br>