The Significance of Funguria in Hospitalized Patients

Completed

• Conditions: Urinary Tract Infections

• Registration Number: NCT00787085
• Lead Sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center

Brief Summary

This investigation is a epidemiologic case-control study of the risk factors associated with nosocomial funguria (fungi in the urine).

Detailed Description

A recent large multi-center national surveillance survey of almost 5000 nosocomial (hospital based) urine isolates from medical intensive care units demonstrated that fungi comprised nearly 40% of urine isolates. Little is known about distinguishing fungi that cause colonization from those causing infection.

The objective of this study is to define the epidemiology of nosocomial funguria and natural history of patients that develop funguria while hospitalized.

Patients who may have eligible for this study will be identified from microbiology laboratory specimens at the Harbor-UCLA Medical Center and Cedars-Sinai Medical Center.

Study Timeline

• Study Start: 2001-09
• Primary Completion: 2006-02
• Study Completion: 2006-02
• Status Verified: 2008-11
• Study First Submitted: 2008-11-06
• Study First Submitted QC: 2008-11-06
• Last Update Submitted: 2008-11-06
• Study First Posted: 2008-11-07
• Last Update Posted: 2008-11-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 919

Inclusion Criteria

• Patients hospitalized at least 12 hours of any age (< 1 day to > 100 years of age) AND a urine or blood culture positive for fungi, OR urine culture negative for fungi (control group)

Exclusion Criteria

• Patients already surveyed for funguria during current hospitalization and patients already being followed for recognized funguria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Funguria	Hospitalization day 0, 3, 7, 14, and every 7 days thereafter until hospital discharge or death

Trial Locations

Locations (2)

Cedars-Sinai Medical Center; 🇺🇸 Los Angeles, California, United States

Harbor-UCLA Medical Center; 🇺🇸 Torrance, California, United States