3D/4D ultrasound guided embryo transfer vs clinical touch technique
Not Applicable
Completed
- Conditions
- InfertilityUrological and Genital DiseasesFemale infertility
- Registration Number
- ISRCTN79955797
- Lead Sponsor
- iverpool Women’s NHS Foundation Trust
- Brief Summary
2020 Abstract results in https://doi.org/10.1002/uog.22315 (added 20/01/2022) 2021 Abstract results in https://doi.org/10.1093/humrep/deab127.082 (added 20/01/2022) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37684296/ (added 06/03/2024)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 320
Inclusion Criteria
1. All women undergoing fresh or frozen embryo transfer
2. All women able to provide written informed consent
Exclusion Criteria
1. Known or suspected hydrosalpinx
2. Fluid within the endometrial cavity
3. Gross distortion of endometrium (e.g. fibroids etc)
4. Previous myomectomy
5. Previous randomization
6. Significant health issues, e.g. HIV, Hepatitis C, Hepatitis B, previous trachelectomy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ive births, recorded at follow up at 10 months
- Secondary Outcome Measures
Name Time Method 1. Biochemical pregnancy, defined as urinary pregnancy test positive, at 2 weeks after embryo transfer<br>2. Clinical pregnancy, defined as presence of intrauterine pregnancy with fetal heart rate >100bpm between 6-8 weeks pregnancy, at 5 weeks after embryo transfer<br>3. Miscarriage, recorded at 20 weeks after embryo transfer<br>4. Ectopic pregnancy, recorded at 8 weeks after embryo transfer<br>5. Multiple pregnancies, recorded at 5 weeks after embryo transfer<br>6. Failed embryo transfer, recorded at time of procedure<br>7. Grading of ease of procedure (Easy 1 to Difficult 5), recorded at time of procedure<br>8. Duration of procedure, recorded at time of procedure<br>9. Patient experience, assessed by questionnaire following procedure