Impact Of Timing Of Drainage Of Massive Ascites On Operative And Post-Operative Course In Living-Donor Liver Transplant Recipients. A Prospective Randomized Controlled Trial.
Not Applicable
Completed
- Conditions
- Massive Ascites
- Interventions
- Procedure: ultrasound guided ascitic fluid drainageProcedure: operative drainage of ascites through small skin incision after induction of anesthesiaDevice: ultrasound
- Registration Number
- NCT02867293
- Lead Sponsor
- Mansoura University
- Brief Summary
Massive ascites is usually controlled over several weeks pre-operatively in liver transplant recipients with the risk of encephalopathy and peritonitis. We hypothesized that intra-operative drainage of ascites will be safe and avoids the inherent risks of pre-operative drainage.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- liver transplant candidates with tense acsites
Exclusion Criteria
- severe coagulpathy (INR more than 2 or platlet count less than 50) MELD more than 20
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Preop-drainage ultrasound ascites drained over the pre-operative week through multiple ultrasound guided paracentesis Preop-drainage ultrasound guided ascitic fluid drainage ascites drained over the pre-operative week through multiple ultrasound guided paracentesis Op-drainage operative drainage of ascites through small skin incision after induction of anesthesia ascetic fluid drained through an abdominal incision after anesthesia
- Primary Outcome Measures
Name Time Method graft survival one year
- Secondary Outcome Measures
Name Time Method patient survival one year
Trial Locations
- Locations (1)
Mansoura university
🇪🇬Mansoura, Dkahleya, Egypt