To Study Effect of the Combination of Midodrine and Tolvaptan (drug) Versus Tolvaptan Alone in Patients With Severe Hyponatremia in Cirrhosis (Liver Disease).
Not Applicable
- Conditions
- Health Condition 1: K769- Liver disease, unspecified
- Registration Number
- CTRI/2021/09/036265
- Lead Sponsor
- Institute of Liver and Biliary Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Child B/C cirrhosis
2) Hyponatremia( severe)
3) Written informed consent
4) Age-18-70 years
Exclusion Criteria
1.AKI(1.5mg/dl)
2.Sepsis
3.Underlyig CKD
4.High risk varices
5.Recent Bleed in 2 weeks
6.Acute Symptomatic hyponatremia
7.SIADH
8.Hypothyroidism
9.Severe cardiopulmonary disease
10.Cerebrovascular accident
11.Multiple strokes;
Pseudohyponatremia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method