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The Effectiveness of Neuropsychological Rehabilitation in Young Dyslexic Adults

Not Applicable
Completed
Conditions
Dyslexia
Interventions
Behavioral: Group based neuropsychological rehabilitation
Behavioral: Individual neuropsychological rehabilitation
Registration Number
NCT01930500
Lead Sponsor
Rehabilitation Foundation, Finland
Brief Summary

The purpose of this study is to determine whether individual and/ group based neuropsychological rehabilitation focused on psychoeducation and teaching compensatory strategies has positive effects on the psychosocial wellbeing and perceived cognitive deficits in dyslexic young adults. The hypothesis is that both individual and group based neuropsychological rehabilitation show positive effects on the psychosocial wellbeing and perceived cognitive deficits. Another purpose of this study is to evaluate weather individual and group based neuropsychological rehabilitation have different kind of effects on the wellbeing of the participants and weather either one of the rehabilitation formats is more effective than the other.

Detailed Description

Background: Untreated dyslexia causes problems for individuals in studies, work and employment. High quality research on the best and most cost-effective rehabilitation methods is needed.

Objective: To study whether neuropsychological rehabilitation improves the psychosocial wellbeing and perceived cognitive deficits in dyslexic young adults and to evaluate potential differences between individual and group based neuropsychological rehabilitation.

Methods: Altogether 120 young adults diagnosed with dyslexia are randomized either to one of the intervention groups (individual neuropsychological rehabilitation / group neuropsychological rehabilitation) or to a control group which will receive either one of the interventions after a 5 month waiting period. All the study subjects are assessed with a short neuropsychological test battery as well as self-rating questionnaires evaluating mood, QoL, perceived cognitive deficits, and the impact of the learning disability at baseline, after five months (immediately after interventions or control period) and after 10 months. After 20 months a shorter follow-up using only self-ratings will be done via mail. Subjects in the intervention groups are offered neuropsychological rehabilitation in 12 sessions conducted once a week or once in two weeks during five months. Subjects in the control group do not receive any intervention for the first five months.

Results: The effects of interventions on psychosocial wellbeing and perceived cognitive deficits are evaluated using appropriate statistical procedures and comparing the differences between the interventions groups and the control group.

The present status: All the interventions are completed, follow-up data is still beeing collected

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
120
Inclusion Criteria
  • clinical diagnosis of dyslexia
  • age 18-35
  • problems in studies, work or employment relating to dyslexia
  • subjective and objective need for rehabilitation
  • the native language is Finnish
Exclusion Criteria
  • other neurological condition than dyslexia
  • other learning disabilities than dyslexia
  • overall weak cognitive capacity
  • psychiatric diagnosis
  • severe depression
  • alcohol or drug abuse
  • neuropsychological rehabilitation received at the age of 16 or later

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Group based neuropsychological rehabilitationGroup based neuropsychological rehabilitation12 times 120 minutes + a brake, once per week or once per two weeks, during 5 months
Individual neuropsychological rehabilitationIndividual neuropsychological rehabilitation12 times 90 minutes, once per week or once per two weeks, during 5 months
Primary Outcome Measures
NameTimeMethod
Subjective reading related performance5 months

Effects of rehabilitation on subjective reading related performance: Adult Reading History Questionnaire (ARHQ) modified

Subjective cognitive performance5 months

The effects of rehabilitation on subjective cognitive performance: Everyday Memory Questionnaire (EMQ)

Secondary Outcome Measures
NameTimeMethod
Verbal fluency and executive control5 months

These cognitive skills are measured using verbal fluency with category switching, Delis-Kaplan Executive Function System; D-KEFS. The score is the total number of correct words generated by the participant within the one-minute time-limit. The range for points is from 0 to as many words as can be generated by the rules within one minute. More points equals a better result.

Quality of life: QOLIBRI-OS5 months

The effects of rehabilitation on quality of life are measured using the Quality of Life after Brain Injury Overall Scale (QOLIBRI-OS). The score ranges from 6-30. More points equals a better quality of life.

Goal achievement5 months

Goal achievement is measures using Goal Attainment Scaling (GAS). The attained goals set at the beginning of the intervention and measured on a scale from -2 to +2 at the end of the intervention. The score is based on a discussion with the therapist and the participant. A score below zero means that the set goal has not been reached. A score of 0 means that the goal has been reached and scores above 0 mean that the goal was reached over expectations.

Social and cognitive behavioral strategies5 months

Strategy and Attribution Questionnaire (SAQ) bref consists of 20 questions using a 7-point-scale (from 1 = "strongly disagree" to 7 = "strongly agree") to assess social and cognitive behavioral strategies.

Processing speed and attention5 months

These cognitive skills are measured using Symbol Digit Modalities test. The score ranges from 0 to 110. More points equals a better result.

Visual fluency and executive control5 months

These cognitive skills are measured using design fluency, Delis-Kaplan Executive Function System; D-KEFS. The score is the total number of correct drawings produced within a minute added togehter from three different one-minute long sessions with different rules. The range for points is from 0 to as many drawings as can be generated by the rules within the three one-minute sessions. More points equals a better result.

Mood5 months

The effects of rehabilitation on mood are measured using Profile of Mood States (POMS). The Finnish version contains 38 questions and the total score ranges from 0 to 152. Less points means a better situation for mood.

Verbal learning5 months

Verbal learning is measured using Word lists subtest (Wechsler Memory Test-III, WMS-III). The total score is between 0 - 48. More points equals a better result.

Reading comprehension5 months

Reading comprehension is measured using V3, a part of a Finnish Ability Test Battery, "Kykytestistö AVO-9". The score ranges fron 0 to 20. More points equals a better result.

Working memory5 months

Working memory is assesed using Digit span sequencing (Wechsler Adult Intelligence Scale - Fourth Edition, WAIS-IV). The total score is between 0 - 16. More points equals better result.

Trial Locations

Locations (1)

Rehabilitation Foundation

🇫🇮

Helsinki, Malminkartano, Finland

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