Effects of Dexmedetomidine and Propofol in brain injury patients

Phase 2

Recruiting

• Conditions: Traumatic brain patients.; Diffuse traumatic brain injury; S06.2

• Registration Number: IRCT20200824048500N1
• Lead Sponsor: Semnan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Traumatic Brain Injury patients (TBI)
Intubation
In ICU
Over 18 years old

Exclusion Criteria

Massive bleeding
Acute or chronic renal failure
Acute or active liver disease
Rheumatologic disorders or auto-immune disease
Acute MI
Hypersensitivity to drugs or egg and Soya

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
euron Specific Enolase (NSE). Timepoint: Before intervention and 24hr after intervention. Method of measurement: Elisa.

Secondary Outcome Measures

Name	Time	Method
S100 calcium-binding protein B (S100B). Timepoint: Before intervention and 24hr after intervention. Method of measurement: Elisa.