EUCTR2022-004079-17-DK进行中（未招募）1 期
Efficacy and safety of 72-hour infusion of Prostacyclin (1 ng/kg/min) in mechanically ventilated patients with infectious pulmonary endotheliopathy– a multicentre randomized, placebo-controlled, blinded, investigator-initiated trial - COMBAT-ARF
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 450
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1.Adult intensive care patients (age = 18 years)
- •2.Suspected pulmonary infection
- •3.Need for mechanical ventilation (< 24 hours from time of screening)
- •4.sTM = 4 ng/mL
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 150
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 300
排除标准
- •1.Withdrawal from active therapy
- •2.Pregnancy
- •3.Septic shock according to Sepsis-3 AND sTM>10 ng/ml
- •4. Known hypersensitivity to iloprost or to any of the other ingredients.
- •5.Previously included in this trial or a prostacyclin trial within 30 days
- •6.Life-threatening bleeding defined by the treating physician
- •7.Known severe heart failure (NYHA class IV)
- •8.Suspected acute coronary syndrome
研究者
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