EUCTR2020-001296-33-DK进行中（未招募）1 期
Efficacy and safety of 72-hour infusion of Prostacyclin (1 ng/kg/min) in patients with COVID-19 induced respiratory failure – a multicentre randomized, placebo-controlled, blinded, investigator-initiated trial
Section for Transfusion Medicine, Capital Region Blood bank, Copenhagen University Hospital0 个研究点目标入组 80 人开始时间: 2020年4月3日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Adult intensive care patients (aged 18 years or above)
- •Confirmed COVID-19 infection
- •Need for mechanical ventilation (< 72 hours)
- •Endothelial biomarker (sTM) = 4 ng/mL
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 25
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 55
排除标准
- •Pregnancy (non-pregnancy confirmed by patient being postmenopausal (age 60 or above) or having a negative urine- or plasma-hCG)
- •Known hypersensitivity to iloprost or to any of the other ingredients.
- •Consent cannot be obtained
- •Previously included in this trial or a prostacyclin trial within 30 days
- •Withdrawal from active therapy
- •Life-threatening bleeding defined by the treating physician
- •Known severe heart failure (NYHA class IV)
- •Suspected acute coronary syndrome
研究者
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