NL-OMON40205
Completed
Not Applicable
Metabolic phenotyping of individuals with abdominal obesity and high levels of hepatic fat before and after dietary interventions - Belly Fat Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- algehele gezondheid, metabole gezondheid
- Sponsor
- Wageningen Universiteit
- Enrollment
- 110
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 40\-70y at the time of recruitment
- •BMI \>27kg/m2 or waist circumference \>102cm (males) or \>88cm (females)
Exclusion Criteria
- •Hb levels \<8\.4 mmol/L
- •Diabetic (normoglycemic according to WHO criteria (OGTT, fasting blood glucose\< 7 mmol/L, after 2 hr \<11\.1 mmol/L)
- •Daily intake of alcohol of \>30g (men) or \>20g (women)
- •Tobacco smoker
- •Abuse of drugs
- •Any medical conditions or (metal) devices interfering with or posing a risk for the participant in 1H\-MRS/MRI scanning (e.g. claustrophobia, pace maker, surgical screws/pins, artificial joints or heart valves, etc.)
- •Diagnosed with any long\-term medical condition (i.e. cardiovascular disease, gastrointestinal disease, renal dysfunction)
- •Use of medications known to interfere with glucose or lipid homeostasis (i.e. corticosteroids)
- •Allergic to fish oil or unwilling to consume fish oil supplements
- •Unwilling to comply with dietary guidelines
Outcomes
Primary Outcomes
Not specified
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