Establishing Pancreatic Fat Content and Pancreatic Volume in Person of Normal glucose tolerance, impaired glucose tolerance and Type 2 Diabetes Mellitus
- Conditions
- Health Condition 1: E119- Type 2 diabetes mellitus without complications
- Registration Number
- CTRI/2023/06/054228
- Lead Sponsor
- A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1:- Normal and Overweight (BMI < 23.0 and >=25 kg/m2)
2:- subjects aged 20-50 years with T2DM of less than 5 year duration with HbA1c 6.5% to 9% & on a stable dose of OHA (metformin and sulphonylurea) over last 8 weeks
3:- Normal and Overweight (BMI < 23.0 and >=25 kg/m2) subjects aged 20-50 years with normal Glucose tolerance matched for age, weight and sex and with no first-degree family history of diabetes.
4:- Normal and Overweight (BMI < 23.0 and >=25 kg/m2) subjects aged 20-50 years with impaired Glucose tolerance matched for age, weight and sex
1:- T2DM patients with poor glycaemic control (HbAâ??c > 9â??0%), hypoglycaemia, diabetic abscess/ulcers, ketoacidosis, pregnant or lactating women, women planning for pregnancy/gestational diabetes,
2:- Subjects with severe cardiac and renal disease, patients with renal transplant /undergoing immunosuppressive therapy for renal transplant ,
3:- Substantial alcohol consumption ( >20 g/day for women or >30 g/day for men),
4:- History of pancreatitis, pancreatic lipomatosis or pancreatic calculi (as detected by ultrasonography) ,
5:- Subjects with type 1 diabetes mellitus,
6:- T2DM Subjects requiring major drug intervention to maintain good glycemic control will be excluded.
7:- Subjects with metallic implants, pacemaker leads, radioactive seeds or surgical staples in the body will be excluded for the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To establish pancreatic volume in normoglycemic , impaired glucose tolerant and person with type 2 diabetes mellitus.Timepoint: 365 days
- Secondary Outcome Measures
Name Time Method To establish pancreatic volume in normoglycemic , impaired glucose tolerant and person with type 2 diabetes mellitus.Timepoint: 365 days