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临床试验/NCT05549986
NCT05549986已完成不适用

Discriminant Ability of the Shock Index, Modified Shock Index, and Reverse Shock Index Multiplied by the Glasgow Coma Scale on Mortality in Adult Trauma Patients: A PATOS Study

Mackay Memorial Hospital0 个研究点目标入组 105,641 人开始时间: 2016年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
105,641
主要终点
Discriminant power of SI, MSI, and rSIG on short-term mortality for adult traumatic patients

研究概览

简要总结

We evaluated a cohort of adult trauma patients transported to emergency departments. The first vital signs were used to calculate the SI, MSI, and rSIG. The areas under the receiver operating characteristic curves (AUROCs) and test results were used to compare the discriminant performance of the indices on short-term mortality and poor functional outcome. A subgroup analysis of geriatric patients, traumatic brain injury, penetrating injury, and non-penetrating injury was performed.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult patients (≥18 years) EMS-transported from January 2016 to December 2020

排除标准

  • Patients with missing entries of age, sex, triage, SBP, DBP, HR, or GCS were excluded.
  • Entries with missing records of in-hospital mortality or 30-day mortality were excluded from the short-term mortality cohort analyses.
  • Patients without a Modified Rankin Scale (MRS) record at discharge were excluded from the functional outcome cohort analyses.

结局指标

主要结局

Discriminant power of SI, MSI, and rSIG on short-term mortality for adult traumatic patients

时间窗: 30 days

AUROC in associated with short-term mortality with SI, MSI, rSIG

次要结局

  • Discriminant power of SI, MSI, and rSIG on functional outcome for adult traumatic patients(We defined no symptoms, no significant disability, slight disability, and moderate disability (MRS 0-3) as favorable functional outcomes and moderately severe disability, severe disability, and death (MRS 4-6) as poor functional outcomes)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Tse-Hao Chen

Principal Investigator

Mackay Memorial Hospital

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