Discriminant Ability of the Shock Index, Modified Shock Index, and Reverse Shock Index Multiplied by the Glasgow Coma Scale on Mortality in Adult Trauma Patients: A PATOS Study

Completed

• Conditions: Trauma; Morality; Shock, Traumatic
• Interventions: Other: Observational

• Registration Number: NCT05549986
• Lead Sponsor: Mackay Memorial Hospital

Brief Summary

We evaluated a cohort of adult trauma patients transported to emergency departments. The first vital signs were used to calculate the SI, MSI, and rSIG. The areas under the receiver operating characteristic curves (AUROCs) and test results were used to compare the discriminant performance of the indices on short-term mortality and poor functional outcome. A subgroup analysis of geriatric patients, traumatic brain injury, penetrating injury, and non-penetrating injury was performed.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01-01
• Primary Completion: 2020-12-31
• Study Completion: 2020-12-31
• Study First Submitted: 2022-08-29
• Status Verified: 2022-09
• Study First Submitted QC: 2022-09-18
• Last Update Submitted: 2022-09-18
• Study First Posted: 2022-09-22
• Last Update Posted: 2022-09-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 105641

Inclusion Criteria

• Adult patients (≥18 years) EMS-transported from January 2016 to December 2020

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Exclusion Criteria

• Patients with missing entries of age, sex, triage, SBP, DBP, HR, or GCS were excluded.
• Entries with missing records of in-hospital mortality or 30-day mortality were excluded from the short-term mortality cohort analyses.
• Patients without a Modified Rankin Scale (MRS) record at discharge were excluded from the functional outcome cohort analyses.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Mortality group	Observational	Patients encountered in-hospital mortality or 30-day mortality
Survival group	Observational	Patients did not encounter in-hospital mortality or 30-day mortality

Primary Outcome Measures

Name	Time	Method
Discriminant power of SI, MSI, and rSIG on short-term mortality for adult traumatic patients	30 days	AUROC in associated with short-term mortality with SI, MSI, rSIG

Secondary Outcome Measures

Name	Time	Method
Discriminant power of SI, MSI, and rSIG on functional outcome for adult traumatic patients	We defined no symptoms, no significant disability, slight disability, and moderate disability (MRS 0-3) as favorable functional outcomes and moderately severe disability, severe disability, and death (MRS 4-6) as poor functional outcomes	AUROC in associated with functional outcome with SI, MSI, rSIG