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Clinical Trials/NCT05549986
NCT05549986CompletedNot Applicable

Discriminant Ability of the Shock Index, Modified Shock Index, and Reverse Shock Index Multiplied by the Glasgow Coma Scale on Mortality in Adult Trauma Patients: A PATOS Study

Mackay Memorial Hospital0 sites105,641 target enrollmentStarted: January 1, 2016Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
105,641
Primary Endpoint
Discriminant power of SI, MSI, and rSIG on short-term mortality for adult traumatic patients
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

We evaluated a cohort of adult trauma patients transported to emergency departments. The first vital signs were used to calculate the SI, MSI, and rSIG. The areas under the receiver operating characteristic curves (AUROCs) and test results were used to compare the discriminant performance of the indices on short-term mortality and poor functional outcome. A subgroup analysis of geriatric patients, traumatic brain injury, penetrating injury, and non-penetrating injury was performed.

Study Design

Study Type
Observational
Observational Model
Cohort
Time Perspective
Retrospective

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Adult patients (≥18 years) EMS-transported from January 2016 to December 2020

Exclusion Criteria

  • •Patients with missing entries of age, sex, triage, SBP, DBP, HR, or GCS were excluded.
  • •Entries with missing records of in-hospital mortality or 30-day mortality were excluded from the short-term mortality cohort analyses.
  • •Patients without a Modified Rankin Scale (MRS) record at discharge were excluded from the functional outcome cohort analyses.

Outcomes

Primary Outcomes

Discriminant power of SI, MSI, and rSIG on short-term mortality for adult traumatic patients

Time Frame: 30 days

AUROC in associated with short-term mortality with SI, MSI, rSIG

Secondary Outcomes

  • Discriminant power of SI, MSI, and rSIG on functional outcome for adult traumatic patients(We defined no symptoms, no significant disability, slight disability, and moderate disability (MRS 0-3) as favorable functional outcomes and moderately severe disability, severe disability, and death (MRS 4-6) as poor functional outcomes)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Tse-Hao Chen

Principal Investigator

Mackay Memorial Hospital

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