Electronic Chromoendoscopy for Polyp Characterization
- Conditions
- Colorectal Polyp
- Interventions
- Diagnostic Test: Prediction of Histology
- Registration Number
- NCT03118856
- Lead Sponsor
- University of Erlangen-Nürnberg Medical School
- Brief Summary
To assess the accuracy of predicting histology of colorectal polyps with electronic chromoendoscopy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 230
- patients undergoing screening or surveillance colonoscopy
- written informed consent
- inadequate bowel preparation
- polyposis syndromes
- history of colectomy
- use of anticoagulants
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description HD-WLE Prediction of Histology Intervention: Prediction of polyp histology with HD-WLE EC Prediction of Histology Intervention: Prediction of polyp histology with EC
- Primary Outcome Measures
Name Time Method Accuracy of predicting histology with EC 1 year Polyps will be visualized in white-light and the location and size will be noted. Afterwards, electronic chromoendoscopy will be used to visualize and enhance the mucosal vascular pattern and the mucosal surface pattern morphology of the polyp. The endoscopist will then make a real time assessment of each polyp according to size, shape, Paris classification and surface characteristics including pit pattern and mucosal vascular pattern morphology, colour, and type of depression. Further, a level of confidence (high or low) will be made for the real time histology prediction. Finally, all polyps will be removed using standard techniques and processed for pathological evaluation and real time and histological results will be compared.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Erlangen
🇩🇪Erlangen, Germany