Virtual Chromoendoscopy for Distal Polyps
- Conditions
- Colorectal Polyps
- Interventions
- Other: Prediction of histology
- Registration Number
- NCT02217449
- Lead Sponsor
- University of Erlangen-Nürnberg Medical School
- Brief Summary
To assess the accuracy of predicting histology with virtual chromoendoscopy for distal colorectal polyps according to the ASGE PIVI statement.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 230
- Written informed consent
- Screening or surveillance colonoscopy
- history of inflammatory bowel disease
- poor bowel preparation
- colectomy
- anticoagulation
- polyposis syndrome
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description HD Prediction of histology Prediction of histology Virtual Chromoendoscopy Prediction of histology Prediction of histology
- Primary Outcome Measures
Name Time Method Effectivity of virtual chromoendoscopy 3 years Upon visualization of a polyp in white-light, the location and size (as compared to open biopsy forceps or snare) are noted. Afterwards, virtual chromoendoscopy is used to visualize and enhance the mucosal vascular pattern and the mucosal surface pattern morphology of the polyp. The endoscopist makes a real time assessment of each polyp according to size, shape, Paris classification and surface characteristics including pit pattern and mucosal vascular pattern morphology, colour, and type of depression. Further, the endoscopist is assigning a level of confidence (high or low) to each real time prediction. Afterwards, all polyps are resected using standard techniques and processed for pathological evaluation. Each polyp is assessed by an experienced GI pathologist blinded to the real time prediction of polyp histology. Finally, real time and histological results are compared.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital Erlangen
🇩🇪Erlangen, Germany