Effectiveness of community level mass drug administration using Albendazole against Taenia solium (pork tapeworm) and other Soil Transmitted Helminths among communities in northern Lao People's Democratic Republic.
Phase 1
Active, not recruiting
- Conditions
- Taenia solium cysticercosisSoil Transmitted HelminthsPublic Health - EpidemiologyInfection - Other infectious diseases
- Registration Number
- ACTRN12614001067662
- Lead Sponsor
- Australian Animal Health Laboratory
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
Any healthy person, male or female, over 6 years old that has given informed consent either personally or via the parent/guardian. People with a cognitive impairment, mental illness or intellectual disability (as indicated by family members) may be recruited as neurocysticercosis is able to cause such conditions.
Exclusion Criteria
Less than 6 years of age, severe illness, non-consenting
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction of parasite burden (Taenia solium and other Soil Transmitted Helminths) compared to the baseline/pre-treatment prevalence data. Faecal samples are processed via microscopy, identification of T. solium antigens (ELISA) and genetic sequencing (PCR). [12 months after the final human drug administration. ]
- Secondary Outcome Measures
Name Time Method Changes in Knowledge, attitudes and practices regarding a range of issues including latrine use, handwashing and pig control. This will be done via qualitative evaluation methodologies, for example outcome mapping and Focus Group Discussions. [12-18 months after the final Albendazole treatment]