Comparison of remimazolam and propofol anesthesia for interventional neuroradiology
Not Applicable
- Conditions
- IV general anesthesia for interventional neuroradiology
- Registration Number
- JPRN-UMIN000047384
- Lead Sponsor
- Seoul National University Bundang Hospital
- Brief Summary
The total phenylephrine dose was lower in the remimazolam group than in the propofol group (p??=??0.001). Hypotensive events were observed in 11 patients in the remimazolam group and 23 patients in the propofol group (p??=??0.001). Recovery times to spontaneous breathing, eye-opening, extubation, and orientation were shorter in the remimazolam group than in the propofol group (all p??<??0.001).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 76
Inclusion Criteria
Not provided
Exclusion Criteria
- A ruptured aneurysm - Multiple aneurysms - History of neuromuscular/cognitive/psychiatric disease (on medication) - Preexisting renal or hepatic dysfunction - Glaucoma
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Total phenylephrine dose required to restore blood pressure during hypotensive events during the procedure
- Secondary Outcome Measures
Name Time Method - The number of hypotension events - Intraoperative remifentanil dose - Time from the end of hemostatic compression to return of spontaneous breathing, time to eye opening, time to extubation, and time to orientation recovery - Time from the end of hemostatic compression to BIS 75, time from flumazenil injection to extubation, time from flumazenil injection to return of orientation (only in remimazolam group) - Intraoperative vital signs