Effect of Eucommia ulmoides capsule on 24-hour blood pressure rhythm in patients with essential hypertensio

Phase 4

Recruiting

• Conditions: essential hypertension

• Registration Number: ITMCTR2100004900
• Lead Sponsor: Institute of Basic Theory of Chinese Medicine, China Academy of Chinese Medicine Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Aged 40-75 years, male or female;
2. Meet the diagnostic criteria of essential hypertension;
3. 24-hour blood pressure rhythm is non-spoon type;
4. The regimen of western medicine for hypertension is stable (more than 3 months);
5. Voluntarily participate in the trial and sign the informed consent form.

Exclusion Criteria

1. People who are known or suspected to be allergic to experimental drugs and their components;
2. Patients with familial hypertension, malignant hypertension, hypertensive emergency, hypertensive crisis and hypertensive encephalopathy;
3. There is evidence of secondary hypertension, including but not limited to the following diseases: unilateral or bilateral renal artery stenosis, polycystic kidney disease, aldosteronism, coarctation of the aorta, Cushing syndrome, pheochromocytoma.
4. Gastrointestinal lesions or gastrointestinal surgery may affect drug absorption or excretion, such as gastroenterectomy, active gastrointestinal inflammation within nearly 3 months, ulcers or gastrointestinal bleeding;
5. Lifestyle with day and night reversal, or irregular sleep patterns;
6. People with a history of alcohol or drug abuse;
7. Inability to cooperate because of neurological or mental disorders;
8. Pregnant, lactating women or people with recent fertility plans;
9. The researchers do not think it is appropriate to participate in this clinical trial;
10. They have participated in other clinical trials within 3 months before the trial.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Effective rate of blood pressure reduction(clinic blood pressure);Blood pressure variability index;Spoon blood pressure recovery rate;

Secondary Outcome Measures

Name	Time	Method
The rate of reaching the standard rate of blood pressure in the clinic;Changes of clinic blood pressure relative to baseline;Changes of home blood pressure monitoring compared with baseline ;