Maintenance Treatment vs. Stepwise Drug Discontinuation After One Year of Maintenance Treatment in First-Episode Schizophrenia

Heinrich-Heine University, Duesseldorf1 site in 1 country71 target enrollmentNovember 2001

Overview

Brief Summary

After one year neuroleptic maintenance treatment in patients with first episode schizophrenia, neuroleptic treatment will be continued vs. stepwise discontinued (randomized design) over a period of 1 year. Under both conditions prodrome based early intervention take place.

Detailed Description

After one year neuroleptic maintenance treatment in patients with first episode schizophrenia, neuroleptic treatment will be continued vs. stepwise discontinued (randomized design) over a period of 1 year. Under both conditions pharmacologic early intervention strategies in case of early sign of relapse will be applied.

Registry

clinicaltrials.gov

Start Date

November 2001

End Date

June 2006

Last Updated

18 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Heinrich-Heine University, Duesseldorf

Eligibility Criteria

Inclusion Criteria

•Patients after 1 year of maintenance treatment after their first-episode in schizophrenia (according ICD-10 F20)
•Age between 18 and 55
•Informed consent
•One year neuroleptic maintenance treatment
•Reaching stable course