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Evaluating the Benefit of Hypnoanalgesia Versus Neuroleptanalgesia During Hand Surgery

Not Applicable
Recruiting
Conditions
Hand Surgery
Interventions
Drug: Neurloeptanalgesic treatment
Other: Hypnoanalgesia
Registration Number
NCT06185829
Lead Sponsor
GCS Ramsay Santé pour l'Enseignement et la Recherche
Brief Summary

This is a single-center, prospective, randomized, open-label study of two parallel groups of patients undergoing hand surgery:

Group 1: locoregional anesthesia + neuroleptanalgesia Group 2: locoregional anesthesia + hypnoanalgesia Therapeutic benefit is based on VAS assessment of intraoperative anxiety.

Detailed Description

In a population of patients undergoing hand surgery and divided into two groups according to the anesthesia protocol administered in addition to locoregional anesthesia by truncal block:

Group 1: neuroleptanalgesia Group 2: hypnoanalgesia Primary objective The main objective of the study is to compare changes in preoperative anxiety between the two groups, between two measurements taken preoperatively (before anxiety management) and at the end of surgery. This level will be evaluated using a VAS rated from 0 to 10.

Secondary objectives

Comparing groups:

* Intraoperative pain

* Total duration of surgical procedure, ICU stay and hospitalization

* Amount of additional sedative treatment administered during surgery

* Post-operative pain

* Patient satisfaction

* Intraoperative and immediate postoperative adverse events

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
64
Inclusion Criteria
  • Patients aged between 18 and 80,
  • Patient who has read and signed the consent form for participation in the study after a reflection period (approximately 15 minutes).
  • Patient applying for outpatient hand surgery under LRA, such as upper limb trunk blocks (flexor teno synovectomy or endoscopic carpal tunnel surgery).
  • Patient requiring sedation associated with locoregional anaesthesia
Exclusion Criteria
  • Contraindication to locoregional anaesthesia or to one of the sedatives used in the protocol
  • Pregnant or breastfeeding patient or woman of childbearing age without highly effective contraception for the duration of the study (surgically sterile, intrauterine device (> 14 days), hormonal contraception (same dose and formulation for at least 6 months), sexual abstinence. Women of childbearing age, i.e. fertile, are considered to be women after menarche and until they become post-menopausal, unless they are permanently infertile or have undergone surgical sterilisation. A post-menopausal state is defined as the absence of menstruation for 12 months without any other medical cause.
  • Patient under court protection, guardianship or curatorship
  • Patient not affiliated to the French social security system
  • Patients unable to understand informed information and/or give written informed consent: dementia, psychosis, disturbed consciousness, non-French-speaking patients, etc.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Usual neuroleptanalgesic treatmentNeurloeptanalgesic treatment-
HypnoanalgesiaHypnoanalgesia-
Primary Outcome Measures
NameTimeMethod
VAS anxiety scoreDay 2

Changes in VAS anxiety score between preoperative and intraoperative assessment.

Anxiety will be assessed on a visual analog scale measuring 10 cm (with 0 = no stress - 10 = major stress) and by administering the APAIS scale.

Secondary Outcome Measures
NameTimeMethod
Treatment SafetyDay 2

The safety will be assessed by collecting data on adverse events occurring during the study.

Pain intensity assessmentDay 2

Pain intensity will be assessed using a simple numerical scale (ENS) graduated from 0 (no pain) to 10 (worst pain imaginable).

Overall patient satisfactionDay 2

Overall patient satisfaction will be assessed using a simple numerical scale (ENS) graduated from 0 (not at all satisfied) to 10 (completely satisfied).

Trial Locations

Locations (1)

Hôpital Privé Paul d'Egine

🇫🇷

Champigny-sur-Marne, France

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