Physiological Response and Visual Attention to Visual Food Images in Healthy Subjects and in Functional Dyspepsia Patients

Not Applicable

Completed

• Conditions: Functional Dyspepsia
• Interventions: Behavioral: visual images

• Registration Number: NCT02727556
• Lead Sponsor: University Hospital Tuebingen

Brief Summary

In functional dyspepsia (FD), abnormal cognitive and emotional changes such increased sensitization, anxiety, and depression scores have been reported in addition to the peripheral changes in gastrointestinal tract functions. In this study, investigators will evaluate the activity of autonomic nervous system, emotional response, and visual attention to food and non-food images in 30 male and female FD patients and 30 age/gender-matched healthy volunteers. These data will provide a new finding of the influence of impaired cognitive processing of food on symptom generation in functional gastrointestinal disorder patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-03
• Study First Submitted: 2016-03-21
• Study First Submitted QC: 2016-04-01
• Study First Posted: 2016-04-04
• Status Verified: 2017-04
• Primary Completion: 2017-04
• Study Completion: 2017-04
• Last Update Submitted: 2017-04-05
• Last Update Posted: 2017-04-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Male and female, volunteering adults BMI: 18-25 kg/m² right-handed Age: 18-65 years Capacity to give informed consent For FD patients, Diagnosis of functional dyspepsia over the last 12 months certified by a medical record Inconspicuous gastroscopy during the last 6 months certified by a medical record

Exclusion Criteria

• Visual impairment Severe psychiatric illness (e.g. schizophrenia, severe depression (BDI-II:29-63)), substance dependence and abuse Intake of antidepressants / antipsychotics

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Functional dyspepsia patient	visual images	Visual stimuli of food and non-food images will be presented to patients. Non-food images include positive, neutral, negative emotional pictures.
Healthy	visual images	Visual stimuli of food and non-food images will be presented to participants. Non-food images include positive, neutral, negative emotional pictures.

Primary Outcome Measures

Name	Time	Method
Psychological response	1-2 years	facial muscle contraction
visual attention	1-2 years	eyemovement

Secondary Outcome Measures

Name	Time	Method
Subjective rating	1-2 years	mood (visual analog scale)

Trial Locations

Locations (1)

Psychosomatic Medicine and Psychotherapy Department, University of Tübingen, Tübingen, Germany; 🇩🇪 Tübingen, Germany