Measurement of Neonatal Microvascular Hemodynamics Using Non-invasive Optical Technologies
- Conditions
- Infant, Premature, Diseases
- Interventions
- Device: Laser Speckle Imaging and Diffuse Optical Spectroscopy
- Registration Number
- NCT01982357
- Lead Sponsor
- University of California, Irvine
- Brief Summary
Alterations to microvascular blood flow in premature infants, are known to contribute to several major disease entities.
The optically-measured tissue blood flow, to determine tissue perfusion that can be use to detect blood loss.
- Detailed Description
The researchers want to use optical technologies to non-invasively detect blood flow that can tell the onset of blood loss. The research can measure blood flow in stable premature infants in the Neonatal Intensive Care Unit over the duration of several weeks.
The technologies are Laser Speckle Imaging and Diffuse Optical Spectroscopy.
Laser Speckle Imaging non-contact imaging technology, is sensitive to blood flow in superficial tissues. Diffuse Optical Spectroscopy, a probe-based contact technology like pulse oximetry, measures hemoglobin concentrations and states deeper below the skin surface.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 32
- premature infants born or transferred to neonatal intensive care unit with a gestational age of 28-35 weeks
- NONE premature infants born or transferred to neonatal intensive care unit
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description premature infant Laser Speckle Imaging and Diffuse Optical Spectroscopy Laser Speckle Imaging and Diffuse Optical Spectroscopy
- Primary Outcome Measures
Name Time Method Normal Blood flow in premature infant up to 4 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
UCIMC
🇺🇸Orange, California, United States