Measurement of Neonatal Microvascular Hemodynamics Using Non-invasive Optical Technologies
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Normal Blood flow in premature infant
研究概览
简要总结
Alterations to microvascular blood flow in premature infants, are known to contribute to several major disease entities.
The optically-measured tissue blood flow, to determine tissue perfusion that can be use to detect blood loss.
详细描述
The researchers want to use optical technologies to non-invasively detect blood flow that can tell the onset of blood loss. The research can measure blood flow in stable premature infants in the Neonatal Intensive Care Unit over the duration of several weeks.
The technologies are Laser Speckle Imaging and Diffuse Optical Spectroscopy.
Laser Speckle Imaging non-contact imaging technology, is sensitive to blood flow in superficial tissues. Diffuse Optical Spectroscopy, a probe-based contact technology like pulse oximetry, measures hemoglobin concentrations and states deeper below the skin surface.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 1 Minute 至 1 Month（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •premature infants born or transferred to neonatal intensive care unit with a gestational age of 28-35 weeks
排除标准
- •NONE premature infants born or transferred to neonatal intensive care unit
结局指标
主要结局
Normal Blood flow in premature infant
时间窗: up to 4 weeks
次要结局
未报告次要终点
研究者
Beckman Laser Institute and Medical Center
Omid Fathi, M.D., Pediatrics
University of California, Irvine