Comparison of Analgesic Efficacy and Occurrence of Emesis Among Different Background Infusion and Bolus Administration Regimens of Fentanyl Based Intravenous Patient-controlled Analgesia in Patients After Laparoscopic Assisted Gastrectomy - a Randomized Blind Study -
Not Applicable
- Conditions
- The Patients With Gastric Cancer Who Are Scheduled to Receive Laparoscopy Assisted Gastrectomy
- Registration Number
- NCT01863355
- Lead Sponsor
- Yonsei University
- Brief Summary
Fentanyl based intravenous patient controlled analgesia(PCA)is popular method for postoperative pain control, but information regarding optimal dose of fentanyl in IV PCA is currently lacking. We thus determine appropriate dose of fentanyl (bolus dose and background infusion rate) for effective pain control with minimal side effects such as nausea and vomiting
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 225
Inclusion Criteria
- Age between 20 and 70
- ASA class I and II
- Gastric cancer patients who are scheduled to receive laparoscopic gastrectomy
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Exclusion Criteria
- Cardiovascular disease(uncontrolled hypertension, unstable angina, congestive heart failure, etc.)
- Renal failure
- Liver failure
- Chronic drug or alcohol abuser
- Anti-cancer chemotherapy
- Chronic opioid use
- Use of antiemetics within 24hrs for nausea and vomiting
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Pain score(VAS) within 48hrs after surgery Pain socre after surgery 1) within 30min-6hrs, 2) within 6-24hrs, 3) within 24hrs-48hrs Pain score after surgery within 48hrs after laparoscopic gastrectomy
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Severance Hospital, Yonsei University Health System
🇰🇷Seoul, Korea, Republic of