NCT01863355Unknown不适用
Comparison of Analgesic Efficacy and Occurrence of Emesis Among Different Background Infusion and Bolus Administration Regimens of Fentanyl Based Intravenous Patient-controlled Analgesia in Patients After Laparoscopic Assisted Gastrectomy - a Randomized Blind Study -
适应症
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 225
- 试验地点
- 2
- 主要终点
- Pain score(VAS) within 48hrs after surgery
研究概览
简要总结
Fentanyl based intravenous patient controlled analgesia(PCA)is popular method for postoperative pain control, but information regarding optimal dose of fentanyl in IV PCA is currently lacking. We thus determine appropriate dose of fentanyl (bolus dose and background infusion rate) for effective pain control with minimal side effects such as nausea and vomiting
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 20 and 70
- •ASA class I and II
- •Gastric cancer patients who are scheduled to receive laparoscopic gastrectomy
排除标准
- •Cardiovascular disease(uncontrolled hypertension, unstable angina, congestive heart failure, etc.)
- •Renal failure
- •Liver failure
- •Chronic drug or alcohol abuser
- •Anti-cancer chemotherapy
- •Chronic opioid use
- •Use of antiemetics within 24hrs for nausea and vomiting
结局指标
主要结局
Pain score(VAS) within 48hrs after surgery
时间窗: Pain socre after surgery 1) within 30min-6hrs, 2) within 6-24hrs, 3) within 24hrs-48hrs
Pain score after surgery within 48hrs after laparoscopic gastrectomy
次要结局
未报告次要终点
研究者
研究点 (2)
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