Monosodium glutamate as a potential trigger for atrial fibrillation - TASTE AF

Academisch Medisch Centrum0 个研究点目标入组 25 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•Reported monosodiumglutamate triggered atrial fibrillation
•Age is between 18 and 80 years
•AF is symptomatic and paroxysmal
•AF was documented on ECG, Holter or pacemaker electrogram at least once in the 6 months preceding presentation
•In sinus rhythm at the moment of study inclusion
•Legally competent and willing and able to sign informed consent
•Willing and able to adhere to the follow up visit protocol

•Myocardial infarction (defined as CKMB> twice upper limit of normal) within the preceding 2 months
•NYHA class IV/IV heart failure symptoms, or class II-III with a recent decompensation requiring hospitalization (unless related to or aggravated by AF)
•Cerebrovascular accident (defined as any sudden neurological deficit lasting longer than 24 hours, with or without pathological changes on the CT cerebrum) with the preceding 6 months
•Known and documented carotid stenosis>80%
•Pregnancy or of childbearing potential without adequate contraception
•Requirement of antiarrhythmic medication for ventricular arrhythmias
•Left ventricular ejection fraction<30%
•Severely enlarged left atrium: left atrial volume index>40 ml/m2 or left atrial diameter>52 mm
•History of previous radiation therapy on the thorax
•Circumstances that prevent follow-up (no permanent home or address, transient, etc.)

发起方