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临床试验/NCT03056404
NCT03056404已完成不适用

Research for Specific Proteins of Interest for the Serological Diagnosis of Bird Fancier's Lung

Centre Hospitalier Universitaire de Besancon2 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2016年6月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
15
试验地点
2
主要终点
number of protein of interest

研究概览

简要总结

This study aims at identifying bird proteins useful for diagnostic tests to determine the cause of Bird Fancier's Lung (BFL).

详细描述

Allergic diseases are an important part of health concerns in Europe and in countries "industrialized". Among them are distinguished from hypersensitivity pneumonitis (HP), consecutive to repeated inhalation of organic substances (bacteria, fungi, avian proteins ...).

As with other HP, the BFL is a invalidating disease, but usually not lethal if the patient reduced sufficiently early exposure to antigens.

Associated symptoms include breathing difficulties a dry cough, a general fatigued state accompanied by a fever and a rapid and pronounced weight loss.

These clinical signs may be similar to a flu-like condition, difficult to discern from other respiratory disease. Diagnosis is based on a set of clinical, radiological and biological arguments that are often discussed.

Using these criteria as predictors would increase opportunities to diagnose HP without using invasive clinical examinations such as biopsy and bronchoalveolar lavage.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • pregnancy and feeding,
  • minor subject,
  • known immunizing deficit

结局指标

主要结局

number of protein of interest

时间窗: 24 months

5 and 15 proteins for all selected birds

次要结局

  • Selection and identification of protein of interest specific for each selected bird(24 months)
  • Selection and identification of proteins of interest common to all selected bird'droppings(24 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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