The Efficacy of Cyanoacrylate on Palatal Wound Healing and Postoperative Complaints
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 35
- 主要终点
- Primary bleeding time
研究概览
简要总结
The palatal donor site of autogenous free gingival grafts significantly influences the patient's morbidity. The purpose of this study was to evaluate the efficacy of cyanoacrylate on palatal wound healing and postoperative complaints.
详细描述
A total of 35 patients were included in the study. In the test group (19 patient), cyanoacrylate was placed over the palatal wounds; conversely, the 16 control group patients were allowed to heal in a conventional way without cyanoacrylate.
Primary bleeding time, presence of secondary bleeding, postoperative pain and completion of epithelization were assessed following free gingival graft operation. As a result, compared to the control group it was determined that the cyanoacrylate tissue adhesive could reduce the postoperative morbidity and improve the wound healing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •no systemic diseases
- •no coagulation disorders
- •no drug intake in the previous 6 months that might effect the periodontal health status
- •no pregnancy or lactation
- •no smoking habit
- •<1 mm attached gingiva width on one or two lower anterior teeth
- •Miller Class I- II- III (Miller 1985) with deep gingival recession (˃ 3mm)
排除标准
- •Hematologic disorders
- •No cooperation
研究组 & 干预措施
Periacryl group
Periacryl, a tissue adhesive, was applied on wound surfaces to achieve haemostasis
干预措施: Free gingival graft (Procedure)
Periacryl group
Periacryl, a tissue adhesive, was applied on wound surfaces to achieve haemostasis
干预措施: Cyanoacrylate application (Procedure)
Control group
Free gingival graft was harvested from palatal region and left to heal without applying periacryl.
干预措施: Free gingival graft (Procedure)
结局指标
主要结局
Primary bleeding time
时间窗: baseline
The moment of active blood flow stasis that a clinical photograph could be taken by examiner without need for suction.
次要结局
- Analgesic consumption(1-7 days after operation)
- Visual Analog Scale (VAS)(1-7 days after operation)
- Completion of epithelization(Once a week for a month after the operation)
研究者
Ceren Gökmenoğlu
Assistant Professor
T.C. ORDU ÜNİVERSİTESİ