Prevention, Management and Rehabilitation of Knee Osteoarthritis at the Workplace

Not Applicable

Not yet recruiting

• Conditions: Knee Pain Chronic; Knee Osteoarthritis; Knee Discomfort
• Interventions: Behavioral: Blood flow restriction (BFR); Behavioral: Usual care (control)

• Registration Number: NCT05822401
• Lead Sponsor: National Research Centre for the Working Environment, Denmark

Brief Summary

The goal of this intervention study is to assess the effect of blood flow restricted (BFR) exercise integrated into the daily work tasks among hospital workers with or at increased risk of chronic knee pain.

The main questions are:

Can BFR exercise integrated into the daily work tasks reduce knee pain (primary outcome) and improve function and work ability among hospital workers with or at increased risk of chronic knee pain? Participants in the intervention group will for shorts bouts during their workdays integrate BFR into their daily work tasks involving walking, whereas the control group will continue as usual.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-04
• Study First Submitted: 2023-04-10
• Study First Submitted QC: 2023-04-10
• Last Update Submitted: 2023-04-10
• Study Start: 2023-04-11
• Study First Posted: 2023-04-20
• Last Update Posted: 2023-04-20
• Primary Completion: 2023-12-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Hospital workers working at least 20 hours per week with or without chronic knee pain (>3 months)

Exclusion Criteria

• Life-threatening disease
• Conditions where BFR training may be contraindicated, e.g. pregnancy, cancer, diabetes, major cardiovascular disease, current, previous or family history of clotting disorders, recent immobilization, major surgery or injections into the joint (i.e. corticosteroid injection)
• Systolic/diastolic blood pressure above 160/100 mmHg

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Blood flow restriction (BFR)	Usual care (control)	Blood flow restricted training (BFR) integrated into the daily work tasks for 8 weeks.
Blood flow restriction (BFR)	Blood flow restriction (BFR)	Blood flow restricted training (BFR) integrated into the daily work tasks for 8 weeks.
Usual care (control)	Usual care (control)	Will continue their work as usual

Primary Outcome Measures

Name	Time	Method
Pain intensity	Change pre-post 8 weeks of intervention	Change in worst knee pain intensity during the last week rated on a 11-point numeric rating scale (NRS)

Secondary Outcome Measures

Name	Time	Method
Functional performance	Change pre-post 8 weeks of intervention	30-s chair-stand test, 40 m fast-paced walk test, a stair-climb test, maximal isometric knee extensor muscle strength
Work ability	Change pre-post 8 weeks of intervention	Single-item on physical work ability derived from the Work Ability Index (WAI)