Interest of Tracheal Extubation in Positive Pressure on Postoperative Oxygenation in Adult Digestive Surgery: Prospective Randomized Study ExPress
Not Applicable
- Conditions
- Patients Undergoing Digestive Surgery With Orotracheal Intubation
- Interventions
- Procedure: positive pressure extubation
- Registration Number
- NCT04381949
- Lead Sponsor
- University Hospital, Rouen
- Brief Summary
Evaluation of a postoperative tracheal extubation protocol under positive pressure in accordance with international recommendations.
Two arms: the first with "classic" extubation with disconnection of the respirator and the second with extubation without disconnection of the respiratory, as recommended.
Computer Randomization with a 1: 1 ration
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 208
Inclusion Criteria
- Age> 18 and <80
- Patient going to benefit from general anesthesia with orotracheal intubation for surgery lasting more than 60 minutes at the visceral surgery unit of the Rouen University Hospital.
- Person affiliated to a social security scheme
- Person who has read and understood the newsletter and signed the consent form
Exclusion Criteria
- Minor patients or age> 80 years
- History of Obstructive Sleep Apnea Syndrome
- Chronic respiratory failure / History of chronic obstructive pulmonary disease
- Surgery < 60 minutes
- Use of methylene blue intraoperatively
- Extubation finally performed in the operating room
- orotracheal intubation difficult to induce general anesthesia
- Suspected inhalation during orotracheal intubation
- Pneumothorax per operative
- Heart failure authenticated by trans thoracic ultrasound <50%
- Neuromuscular pathologies (myasthenia gravis, myopathies)
- Body mass index> 35
- Emergency surgery
- Patient with an ASA IV score (ie according to the definition of the American Society of Anesthesiology)
- Major surgical complications (hemorrhagic shock)
- Major anesthetic complications (anaphylactic shock, bronchospasm)
- Pregnant or parturient or lactating woman or woman of childbearing age without proven contraception
- Person deprived of their liberty by an administrative or judicial decision or person placed under the protection of justice / guardianship or curatorship
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Positive pressure extubation arm positive pressure extubation -
- Primary Outcome Measures
Name Time Method Desaturation rate within one hour of tracheal extubation defined by a SpO2 \< 92%
- Secondary Outcome Measures
Name Time Method