Effect of Cuff Pressure During Operation on Postoperative Sore Throat
试验速览
- 阶段
- 不适用
- 入组人数
- 138
- 主要终点
- postoperative sore throat
研究概览
简要总结
When general anesthesia is performed for surgery, tracheal intubation is performed. In order to ventilate after performing tracheal intubation, air is injected into the cuff attached to the tube to fill the gap between the tracheal tube and the patients's inner surface of trachea.
Even though, 20 to 30 cm H2O is known to be the appropriate pressure to prevent air leaks while preventing ischemic damage of tracheal mucosa. So, Researchers want to observe clinical differences in pressure at both ends of the safety zone of the cuff pressure.
详细描述
Patients who are scheduled for elective surgery/ general anesthesia are randomized to two groups.
l : cuff pressure - 20cmH2O ll : cuff pressure - 30cmH2O
After tracheal intubation with routine method, cuff pressure is continuously monitored with manometer. The anesthesia during surgery is maintained with 0.8 MAC of desflurane and continuous remifentanil. Clinical outcomes (sore throat, hoarseness and postoperative pain) are evaluated after 0 minutes, 2 hours, 4 hours, and 24 hours after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients undergoing total hip replacement arthroplasty that require general anesthesia
排除标准
- •a patient who disagrees with the study
- •tracheal stenosis
- •operation time > 3 hours or < 1 hour 30 minutes
- •difficult airway
- •drug abuse, alcoholism
结局指标
主要结局
postoperative sore throat
时间窗: At postoperative 24 hours
Number of participants with postoperative sore throat for postoperative 24 hours
次要结局
- postoperative hoarseness(At postoperative 24 hours)
- nausea(At postoperative 24 hours)
- Requirements of analgesics(At postoperative 24 hours)
研究者
Jiwon Lee
assistant professor
Keimyung University Dongsan Medical Center