Histamine Release and Implications of H1- and H2-Blockade in Adult Cardiac Surgery - A Randomised Controlled Study
Completed
- Conditions
- Cardiovascular diseaseCirculatory SystemCoronary artery bypass grafting and valve surgery
- Registration Number
- ISRCTN28343638
- Lead Sponsor
- niversity of Wales College of Medicine, UK
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
Entry criteria: Patients presenting for elective coronary artery bypass grafting (CABG) and valve surgeries using cardiopulmonary bypass.
Exclusion Criteria
1. Patients on heparin or nitrate infusions
2. Patients with known allergies
3. Known asthmatics and patients with severe chronic obstructive pulmonary disease (COPD)
4. Patients on steroids or other immunosuppressive drugs
5. Emergency procedures or re-do operations
6. Patients on regular H1 or H2 blockers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ot provided at time of registration
- Secondary Outcome Measures
Name Time Method ot provided at time of registration