The Impact of Dietary Histamine in Chronic Pain – Pilot Study

Not Applicable

• Conditions: Chronic pain; Anaesthesiology - Pain management

• Registration Number: ACTRN12624000643572
• Lead Sponsor: GenIMPACT, Macquarie University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-20
• Last Update Posted: 27 May 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

(a)All patients aged 18 years and over referred to Pain Management Research Centre at Royal North Shore Hospital
(b) Adults (age 18 years and over)
(c) Patient-reported food allergy or intolerance and/or GI pain, discomfort, or bloating, and
(d) Multi-site pain (2 or more sites), and
(e) Chronic pain (at least 3 months)

Exclusion Criteria

(a) Any active cancer
(b) Inability to read or speak English sufficiently
(c) Patients seeking further medical/ surgical interventions for pain

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in pain[Pain scores on the 4-item pain severity subsection of the Brief Pain Inventory (BPI). Baseline and 4 weeks post commencement of dietary intervention]

Secondary Outcome Measures

Name	Time	Method
Change in quality of life outcome[Assessment of Quality of Life (AQoL-8D) utility score. Baseline and 4 weeks post commencement of dietary intervention];Depression[Scores on the Depression Anxiety and Stress Scale 21 (DASS-21) Baseline and 4 weeks post commencement of dietary intervention]