Investigating the effects of recommended - but unproven - therapies for anaphylaxis in a human histamine challenge model

Not Applicable

• Conditions: Shock; Not Applicable

• Registration Number: ISRCTN11335622
• Lead Sponsor: Medical University of Vienna

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-05
• Last Update Posted: 19 August 2024
• Study Completion: 2030-01-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 0

Inclusion Criteria

Healthy volunteers

Exclusion Criteria

1. Non-healthy
2. Pregnant
3. Breastfeeding

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean arterial blood pressure measured with an automated device over 15 minutes during histamine infusion

Secondary Outcome Measures

Name	Time	Method
1. Diastolic and systolic blood pressure with an automated device measured over 15 minutes during histamine infusion<br>2. Pharmacokinetics of adrenaline measured with qualified mass spectrometry assays over 60 minutes