Conditioning Antihistamine

Completed

• Conditions: Itch, conditioning; Jeuk, conditioneren

• Registration Number: NL-OMON27241
• Lead Sponsor: eiden University

Brief Summary

n/a

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 92

Inclusion Criteria

1. Between 18 and 35 years old;

2. Good understanding of written and spoken Dutch;

Exclusion Criteria

1. Current psychiatric (DSM-IV) conditions;

2. All somatic conditions that might interfere with the participant’s safety and/or study protocol (e.g. asthma);

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary study parameter is the difference in self-reported mean itch during a validated histamine test (iontophoresis) between the conditioned groups and the placebo group. Itch will be assessed by means of a numeric rating scale (NRS).

Secondary Outcome Measures

Name	Time	Method
Secondary study outcomes include pulmonary functioning and wheal size, flare response, skin temperature, and self-reported skin condition following histamine iontophoresis. Scratching behavior during and following histamine iontophoresis will be assessed as well.