Melatonin vs Gabapentin for Post Trauma Surgery
- Conditions
- Anxiety, Preoperarative
- Interventions
- Registration Number
- NCT05699876
- Lead Sponsor
- All India Institute of Medical Sciences, New Delhi
- Brief Summary
This project aims to compare the effect of preoperative administration of melatonin and gabapentin in reducing preoperative anxiety, stress markers and postoperative pain levels in trauma patients undergoing surgery. Gabapentin has analgesic as well as sedative properties. Melatonin, a hormone has been extensively used in intensive care units and has found to improve the sleep cycle and reduce pain. It is now being explored as a preoperative medication.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 70
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Melatonin Melatonin 6 MG - Gabapentin Gabapentin -
- Primary Outcome Measures
Name Time Method preoperative anxiety 30 minutes after drug administration evaluate the difference in the preoperative anxiety score(Numerical Rating Scale ) before and after drug administration
- Secondary Outcome Measures
Name Time Method post operative analgesia 24 hours postoperative o Total fentanyl consumption 24 hours post-surgery
inflammatory markers before and 30 minutes after drug administrartion o The serum cortisol and IL6 levels (biochemical markers of stress) intraoperatively and postoperatively
Sedation score before and 30 minutes after drug administrartion Sedation score based on Observer Assessment of Alertness/Sedation Scale (OAA/S) before and after drug administration
Trial Locations
- Locations (1)
Aiims
🇮🇳New Delhi, Delhi, India