Retrospective analysis of the transcortical and transcallosal resection of ventricle tumors

• Conditions: D33.0; D43.0; Brain, supratentorial

• Registration Number: DRKS00021453
• Lead Sponsor: eurochirurgische KlinikUniversitätsklinikum Erlangen

Brief Summary

Transcallosal surgery was associated with a higher probability of neurological deficits and memory impairment in our series. However, it had less surgical complications with similar GTR and seizure rates.

Detailed Description

Not available

Study Timeline

• Study Completion: 2023-04-01
• Study Start: 2023-04-24
• Results First Posted: 2023-08-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Retrospective analysis of patients operated between January 1st, 2005 and December 31st, 2020.

1. Age of at least 18 years
2. Lesions growing within or adjacent to the ventricles operated via a transcortical or transcallosal approach
3. Ability to understand, provide, and sign the informed consent
4. Length of follow-up: minimum of 1 year

Exclusion Criteria

1. Subjects under arrest or in a lawsuit
2. Incompleteness of data
3. Poor MRI image quality

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of surgery, tumor removal (complete/incomplete), intraoperative parenchymal damage (infarction, hemorrhage), tumor characteristics (size, histology, invasion, localization), postoperative epileptic seizure occurrence, speech and memory disturbances, postoperative neurological deficits, overall mortality.

Secondary Outcome Measures

Name	Time	Method
Rate of re-operations, postoperative infection rate, hydrocephalus rate, pre- and postoperative neurological status (Karnofsky Performance Score, Glasgow Outcome Score), quality of life and overall health status (German Version of SF-36 inventory, Nottingham Health Profile).