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临床试验/NCT07429981
NCT07429981已完成不适用

Investigation of the Effectiveness of Nerve Gliding Exercises in Individuals With Cervical Radiculopathy

Zonguldak Bulent Ecevit University1 个研究点 分布在 1 个国家目标入组 26 人开始时间: 2026年4月1日最近更新:
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
26
试验地点
1
主要终点
Visual Analog Scale (VAS)

研究概览

简要总结

The aim of this study is to investigate the effect of nerve gliding exercises on pain, cervical range of motion, joint position sense, grip strength, functional status and quality of life in individuals with cervical radiculopathy.

详细描述

The cervical spine is not only the most mobile region of the spine, but also acts as a functional bridge between the head and the torso, consisting of a total of seven vertebrae. The vertebrae in this region are relatively small in size and have a high capacity for movement due to the need for a wide range of joint motion; these characteristics allow for free movement of the head and enable optimal head-neck positioning in response to environmental stimuli.

Mechanical compression, irritation or inflammation of the cervical nerve roots results in a clinical picture of cervical radiculopathy (broadly defined as cervical neuropathy). This condition presents with symptoms such as pain radiating from the neck to the upper extremities, paraesthesia, muscle weakness and sensory loss. Spondylotic changes in the mobile cervical segments can lead to a decrease in intervertebral disc height, disc protrusion, and degenerative changes in the facet joint capsule.

In cervical radiculopathy, patients may only complain of upper extremity pain; however, they report significant difficulties in functions such as hand-eye coordination, gross and fine grip strength, dressing, and heavy lifting. Indeed, in radiculopathy, in addition to pain and sensory changes, decreased grip strength and reduced upper extremity function are frequently observed findings.

The specific clinical presentations at the root level vary. In C5 root involvement, pain radiates from the end of the cervical level over the shoulder to the upper lateral aspect of the arm; involvement of the deltoid and biceps muscles may cause painful limitation in shoulder abduction and elbow flexion. Degenerative disc disease most commonly affects the C5-6 and C6-7 levels. In C6 root compression, pain starts in the lower part of the neck and extends to the biceps, lateral forearm, and dorsal hand/fingers; it is often accompanied by pain in the proximal arm and sensory deficit in the hand. The most common cause of C7 root radiculopathy is disc herniation; pain in the back of the shoulder and dorsolateral arm with decreased triceps reflex is typical; triceps weakness during overhead activities may be a prominent complaint. The flexor carpi radialis, pronator teres, extensor digitorum communis, and latissimus dorsi may also be affected. The C8 root innervates sensation in the ulnar side of the forearm and hand; compression may cause pain and numbness similar to ulnar nerve lesions. With involvement of the flexor digitorum profundus/superficialis and intrinsic hand muscles, finger flexion and abduction become difficult; weakness of the first dorsal interosseous muscle impairs fine hand skills (e.g., turning a key, holding small objects) and reduces grip strength.

The primary goals of rehabilitation are to reduce pain, preserve nerve function, increase range of motion, and improve quality of life. Among conservative approaches, neural gliding/sliding exercises have gained increasing prominence in recent years. These exercises are targeted manual/exercise-based applications that aim to increase the relative movement of compressed nerve tissue in relation to surrounding tissues; they are reported to improve transmission by reducing intraneural pressure, increase intraneural circulation, and improve the mobility of the connective tissue surrounding the nerve. These mechanisms target pain reduction, increased functional capacity, and improved nerve mobility.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

盲法说明

The researcher who will evaluate the patients before and after treatment will not know which group the patients are in.

入排标准

年龄范围
18 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Have been diagnosed with cervical radiculopathy by a specialist physician
  • Have disc herniation at the C5-C6, C6-C7 or C7-T1 level according to imaging (magnetic resonance imaging, MRI) findings (in the bulging or protrusion stage)
  • Have unilateral nerve root involvement

排除标准

  • Predominance of primary peripheral entrapment neuropathy (carpal/cubital/radial tunnel, etc.)
  • Multiple nerve root involvement
  • Progressive neurological deficit
  • History of trauma or surgery to the cervical and upper extremity region
  • Systemic disease contraindicating exercise
  • Pregnancy
  • Manual therapy, injection, or regular physiotherapy applied to the cervical region within the last 3 months
  • Cognitive/psychiatric condition preventing compliance with the assessment protocol

研究组 & 干预措施

Control Group

Active Comparator

Conventional rehabilitation program (isometric neck strengthening exercises, neck stretching exercises) for cervical radiculopathy.

干预措施: Convantional rehabilitation (Other)

Intervention Group

Experimental

Conventional rehabilitation program (isometric neck strengthening exercises, neck stretching exercises) for cervical radiculopathy and neuromobilization exercises.

干预措施: Neuromobilization (Other)

结局指标

主要结局

Visual Analog Scale (VAS)

时间窗: 3 weeks

The Visual Analog Scale (VAS) will be used to evaluate pain for rest, activity and night periods. The data will be recorded in centimeters.

次要结局

  • Cervical range of motion (CROM)(3 weeks)
  • Nerve cross-sectional area (CSA)(3 weeks)
  • Cervical joint position sense(3 weeks)
  • Nerve excursion measurement(3 weeks.)
  • Deep cervical flexor muscle endurance(3 weeks)
  • Gross grip strength(3 weeks)
  • Pinch grip strength(3 weeks)
  • Neck Disability Index(3 weeks)

研究者

发起方
Zonguldak Bulent Ecevit University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Eda AKBAŞ

Associate Professor

Zonguldak Bulent Ecevit University

研究点 (1)

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