Effectiveness of Cognitive Rehabilitation on Cognition and Quality of Life in Chemotherapy-Induced Cognitive Impairment- A Randomized Control Trial. - NI

Ravi Nair Physiotherapy College0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年4月29日

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•1)Newly diagnosed patients with stages I to III cancers planning to receive a definitive number of platinum-based compounds chemotherapy.
•2)Patients who are given Taxanes and Platinum-based compounds – Cisplastin, Carboplatin and Oxaliplatin
•3)3) Patients having Grade I or II cognitive impairment according to National Cancer Institute –common toxicity criteria.
•4)Planned to receive a minimum of 4 cycles of chemotherapy treatment with either of the chemotherapy agents (Platinum based compound)
•5)Both Male and female aged grouped between 14-70 years.
•6)Patients who are given drugs according to approval of national cancer board

•1)Patients having Pre-existing cognitive impairment.
•2)Patient having Traumatic Brain Injury.
•3)Patients having a previous history of any psychological condition that could impair cognitive function.
•4)Patients who did not perceive any chemotherapy cycle after cancer treatment.
•5)Patients with a previous history of cancer and chemotherapeutic drugs.
•6)Those who were having any neurological disorders in the brain and spinal cord such as Alzheimer’s disease (AD), Lewy body disease, stroke (CVA), Huntington’s disease, MS, ALS, frontotemporal dementia, and vascular dementia; use of medication known to have a negative impact on cognition (benzodiazepines).
•7)Use of antipsychotics and cholinesterase inhibitors (CHEIs); current or recent (past 6 months) alcohol or substance use disorder; any behavioural changes like depression, anxiety, stress, other systemic diseases likely to impair cognition, such as hypothyroidism, de ?ciency of folic acid or vitamin B12, or viral infection (syphilis, HIV); vision and speech impairment (aphasia).

发起方

Ravi Nair Physiotherapy College