The comparative study of symptom improvement according to proton pump inhibitor therapy approaches in laryngopharyngeal reflux disease patient

Hallym University Medical Center-Dongtan0 个研究点目标入组 72 人开始时间: 待定最近更新: 2020年4月21日

适应症

试验速览

暂无简介。

•(1) Patients over 18 year
•(2) Those with above 13 and 7 score in reflux symptom index and reflux finding score and have laryngopharyngeal reflux disease in larynx endoscope
•(3) Patients who agree to participate in this study voluntarily

•(1) The highly sensitive person to proton pump inhibitor
•(2) Those with the malignant tumor or infection of the larynx
•(3) Those with need to take steroids or aspirin (more than 325mg/d), warfarin, coumarin during this study constantly
•(4) Those who has undergone surgery or treatment for gastroesophageal reflux disease
•(5) Those who has undergone gastric acid suppression surgery or gastro-duodenal surgery
•(6) Those who has undergone major surgery affecting gastric acid secretion
•(7) Those with the history of administration with other proton pump inhibitor or H2-blocker within 3 months
•(8) Psychiatric patient, alcohol addictor or those with the history of drug abuse
•(9) Pregnant and lactating women
•(10) Childbearing women (Menopausal women who are amenorrheic for at least 12 months are considered to be non-childbearing women.)
•(11) Those who participated in other clinical trial within 6 months before screening
•(12) Those who are judged to be improper for this clinical trial

发起方

Hallym University Medical Center-Dongtan