A study on the Role of Rotational Thromboelastography in management of Traumatic Brain Injuries

Traumatic brain injury is one of the most common cause of death and disability in road traffic accidents. Damage to cerebral parenchyma leads to coagulopathy due to increased tissue factor release, disseminated intravascular coagulation, quantitative and qualitative platelet deficits and activation of protein C pathways. Standard coagulation tests are used to identify coagulopathy but they generally provide inadequate information on complete hemostasis. To overcome this, viscoelastic studies like Rotational thromboelastometry are being implemented in traumatic brain injuries which provide real time information regarding coagulation, right from initiation to fibrinolysis, which inturn help in goal-directed coagulopathic correction.Targeted coagulopathic correction could lead to better outcome.Viscoelastic studies in trauma ,cardiac and liver surgeries have proved to decrease perioperative bleeding and use of blood products with targeted therapy. This study will help in evaluating  the usefulness of Rotational thromboelastometry in patients undergoing craniotomy in isolated traumatic brain injuries