Chest Dysphoria in Transmasculine Spectrum Adolescents

Completed

• Conditions: Gender Dysphoria
• Interventions: Procedure: Mastectomy and chest masculinization

• Registration Number: NCT04195659
• Lead Sponsor: Northwestern University

Brief Summary

The investigators hypothesize that masculinizing top surgery (e.g., mastectomy and chest masculinization) leads to an improvement in self-report chest dysphoria, gender dysphoria, and gender congruence in assigned-female-at-birth, transgender and non-binary youth and young adults. This is a prospective, observational study that will enroll assigned-female-at-birth, transmasculine spectrum individuals age 13 to 25 years old who are or are not undergoing top surgery. Participants will complete a set of standard of care questionnaires regarding their chest dysphoria (e.g., distress about the chest), gender dysphoria (e.g., distress about a gender identity that does not match assigned sex), and gender congruence (e.g., degree to which an individual feels they are living in their authentic appearance and gender identity). They will complete this same set of questionnaires either three months after their top surgery or three months after the initial set of surveys.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2019-10-29
• Study First Submitted: 2019-12-10
• Study First Submitted QC: 2019-12-11
• Study First Posted: 2019-12-12
• Primary Completion: 2021-12-31
• Study Completion: 2021-12-31
• Status Verified: 2022-06
• Last Update Submitted: 2022-06-08
• Last Update Posted: 2022-06-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 81

Inclusion Criteria

• Assigned the female sex at birth
• Affirmed gender identity of male, non-binary, or gender other than female
• English-speaking
• Undergoing top surgery or matches a top surgery participant on age and number of months on testosterone

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Exclusion Criteria

• Non English speaking
• Unable to complete self-report questionnaires

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Top Surgery	Mastectomy and chest masculinization	Individuals assigned the female sex at birth, who identify as a gender other than female, are between the ages of 13 and 25 years, and who are undergoing mastectomy and chest masculinization in one of three plastic surgery practices in Chicago.

Primary Outcome Measures

Name	Time	Method
Chest Dysphoria	Three month	The disruption of individual comfort, physical functioning, and interpersonal relationships from a chest with breasts, as measured by the Chest Dysphoria Measure (Score 0-51, Higher number means greater chest dysphoria)

Secondary Outcome Measures

Name	Time	Method
Gender Dysphoria	Three month	Distress about a gender identity that differs from assigned sex, measured by the Utrecht Gender Dysphoria Scale (Score 12-60, Higher number means greater gender dysphoria)
Gender Congruence	Three month	Feelings of living in an authentic gender identity and appearance, as measured by the Kozee Transgender Congruence Scale (Score 12-60, Higher number means greater gender congruence)

Trial Locations

Locations (3)

Ann and Robert H Lurie Children's Hospital of Chicago; 🇺🇸 Chicago, Illinois, United States

University of Illinois Chicago; 🇺🇸 Chicago, Illinois, United States

Northwestern University; 🇺🇸 Chicago, Illinois, United States