Diagnostic accuracy of urine sodium after normal saline treatment in hyponatremia patient

Recruiting

• Conditions: non edematous hyponatremia patient; Hyponatremia, Urine sodium, Diagnostic accuracy

• Registration Number: TCTR20221204002
• Lead Sponsor: o sponsor

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-12-04
• Study Completion: 2024-05-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

1. Serum sodium <130 meq/L
2. Serum osmolality < 280 mOsm/kg H2O
3. No clinical sign of volume overload (no pulmonary edema, no ascites, no edema)
4. Primary doctor plan to give 0.9%NaCl infusion of at least 500 ml or 3%Nacl infusion of at least 150 ml

Exclusion Criteria

1. Received treatment of hyponatremia ex. NaCl infusion, Diuretics, NaCl tab before
2. Patients with hypothyroid
3. Patients with adrenal insufficiency
4. Patients with chronic diuretic therapy
5. Patients with chronic kidney disease(eGFR<60 ml/min/1.73m2)
5. Cannot collect urine sample in accordance with study protocol
6. known bladder dysfunction or urinary incontinence

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity and specitivity of urine sodium after normal saline treatment After normal saline infusion 500 ml Percent

Secondary Outcome Measures

Name	Time	Method
Sensitivity and specitivity of urine sodium after normal saline infusion 1,000 ml After normal saline infusion 1,000ml Percent,Sensitivity and specitivity of urine osmole after normal saline infusion 1,000 ml After normal saline infusion 1,000ml Percent,Sensitivity and specitivity of urine osmole after normal saline infusion 500 ml After normal saline infusion 500 ml percent