Evaluation of Dialectical Behavior Therapy (DBT)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 86
- 试验地点
- 2
- 主要终点
- Urinalysis
研究概览
简要总结
The purpose of this study is to compare a one year treatment program of Dialectical Behavior Therapy (DBT) + suboxone for opiate addicted individuals meeting criteria for borderline personality disorder (BPD) to a one year program of standard drug counseling (I/GDC) + suboxone.
详细描述
The purpose of this study is to compare a one year treatment program of Dialectical Behavior Therapy (DBT) + suboxone for opiate addicted individuals meeting criteria for borderline personality disorder (BPD) to a one year program of standard drug counseling (I/GDC) + suboxone. Drug counseling consists of manualized individual sessions + group therapy. This trial is being completed at two sites, at the University of Washington and at Duke University. One hundred and seventy-two individuals (86 per condition) with opiate dependence and meeting criteria for BPD will be enrolled in a one-year treatment and a one-year follow-up assessment. Each site (University of Washington, Duke) will enroll 86 clients with both treatment conditions being conducted at each site. Assessments measuring drug use, suicidal behaviors, retention and other treatment-related behaviors, general psychopathology and functioning, and increases in behavioral skills will be given at four month intervals for the entire two years.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Meets SCID-I criteria for opiate dependence.
- •Meets IPDE and SCID criteria for BPD (DSM-IV)
- •Over 18 years old
- •Resides within commuting distance of treatment
- •Consents to outpatient treatment for drug addiction
排除标准
- •Bipolar, Schizophrenia, Schizophreniform, or Schizoaffective Disorders, Psychosis NOS
- •IQ less than 70; life threatening anorexia; current and chronic absence of shelter; impending jail/prison for more than three weeks (problems which by their presence or severity preclude ability to attend or understand treatment and/or requires priority treatment over SUD treatment)
- •Court order to treatment, court order to treatment or to jail, or agency order to treatment or loss of child custody (due to consequent inability to freely drop-out of treatment)
- •Is pregnant, plans to become pregnant during treatment phase, or becomes pregnant before random assignment to study condition
- •Is unable to tolerate suboxone induction phase
- •Is currently stable on methadone
- •Current benzodiazepine use from which the participant is unwilling to taper
- •Refuses: to discontinue current mental health or drug abuse treatment or random assignment.
研究组 & 干预措施
Dialectical Behavior Therapy
Participants receive standard dialectical behavior therapy and suboxone
干预措施: Dialectical Behavior Therapy (Behavioral)
Drug Counseling
Participants receive standard individual and group counseling and suboxone.
干预措施: Drug Counseling (Behavioral)
结局指标
主要结局
Urinalysis
时间窗: one year treatment, one year follow-up
次要结局
- Suicidal Behavior(one year treatment, one year follow-up)
- Depression, anxiety, Axis I diagnostic remission(one year treatment, one year follow-up)
研究者
Marsha Linehan
Professor
University of Washington