Effect of high-intensity interval training and moderate-intensity continuous training on ambulatory blood pressure, cardiac, vascular, autonomic, cerebral, psychological, metabolic and body composition outcomes in hypertensive older adults: a randomized controlled clinical trial - HEXA: Hypertension EXercise Approaches: an intervention study in older patients

niversidade Federal do Rio Grande do Norte – UFR0 个研究点开始时间: 2019年4月2日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•Both sexes; aged 60-80 years; previous diagnosis of hypertension; self-reported and clinically assessed physical activity readiness; unchanged pharmacological plan for hypertension in the last 4 weeks; willing to engage in any of the interventions; not engaging in a regular physical activity program in the past 3 months; insufficiently active (i.e., not performing 150 min/week of moderate physical activity and/or 75 min/week of vigorous physical activity, assessed through 7-day accelerometry)

•Being unable or refusing to sign the consent form; previous cardiovascular events or diseases (e.g. unstable angina, severe arrhythmia, acute myocardial infarction, coronary artery disease, stroke, deep vein thrombosis, peripheral artery disease, uncontrolled arrhythmia, pacemaker use, etc.); limiting chronic pulmonary disease (emphysema, chronic bronchitis, asthma); chronic kidney disease in need of dialysis; incidence of cardiovascular or pulmonary events during the study; uncontrolled hypertension (> 160/105 mmHg); diabetes with insulin use or decompensated (fasting glucose > 300 mg/dl); high alcohol intake (>14 doses per week); self-reported or perceived language, hearing or sight limitations that may come to hinder participation; exercise contraindication, as indicated on the maximum cardiopulmonary exercise test (e.g. EKG alterations suggesting myocardial ischemia); osteomioarticular issues that may prevent performing maximal cardiopulmonary exercise testing and moderate-to-vigorous aerobic exercise or osteomioarticular injury during the study (e.g. muscle injury resulting in limitations for exercise); neurological progressive disorders (Parkinson, multiple sclerosis, Alzheimer); cancer demanding treatment in the past two years

发起方

niversidade Federal do Rio Grande do Norte – UFR